metsoako ea meriana 99% phofo ea bohloeki CAS 86386-73-4 Fluconazol
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Litaba tsa Motheo
Fluconazole-D4 e bonahala e le phofo e tšoeu ho isa ho e mosehla-tšoeu ea kristale 'me e nkha hanyenyane ka tatso e babang.
E qhibiliha ha bonolo ka glacial acetic acid, methanol kapa ethanol, ha e khone ho qhibiliha ka metsing 'me e batla e sa qhibilihe ka har'a ether ha ntlha ea ho qhibiliha e le 137~141.6 ℃, kapa ntlha e qhibilihang e le 138~140 ℃ (e nkiloeng ho ethyl acetate-hexane).
Tšebeliso
Sehlahisoa sena ke sa fluorinated triazole antifungal drug le antifungal spectrum e tšoana le ketoconazole empa ts'ebetso ea antifungal e phahame ho feta ketoconazole.
Mokhoa oa eona oa ts'ebetso ke ho thibela karolo ea bohlokoa ea fungal cell membrane, ergosterol biosynthesis enzyme, ho thibela motsoako oa ergosterol le ho senya botšepehi ba lerako la lisele tsa fungal, ho thibela kholo ea bona le ho ikatisa le ho feta.
Sehlahisoa se na le ts'ebetso e matla ea antifungal khahlano le Candida albicans, Microsporum canis, Cryptococcus neoformans, histoplasma capsulatum le epidermophyton.
Lintho tsa Lik'hemik'hale
Fluconazole-D4 e Tiileng ho Tsoela Pele ho Bosoeu
E Sebelisa Lebeletsoeng Fluconazole (F421000).E sebelisoa e le antifungal.
E sebelisa anticholinergic
Fluconazole-D4 e sebelisoa ho phekola mafu a fungal.
E sebelisa A triazole broad-spectrum antifungal agent.
Lipontšo
Fluconazole (Diflucan) e ka 'na ea kenngoa hamolemo' me mohlomong ha e na hepatotoxic e fokolang ho feta ketoconazole, empa e theko e boima haholo, e leng taba ea bohlokoa ha ho nahanoa ka bolelele bo hlokahalang ba phekolo bakeng sa mafu a mangata a fungal a letlalo.