Nimetazepam CAS: 2011-67-8 hypnotic tranquilizer

Nimetazepam ke hypnotic e sebetsang e mahareng, e tsoang ho benzodiazepine.E qalile ho etsoa ka 1964 ke sehlopha sa Hoffmann-La Roche.E na le matla a hypnotic, anti-anxiety, khutso le litlamorao tsa ho phomola mesifa ea masapo.Nimetazepam e boetse e le anticonvulsant e sebetsang ka ho khetheha.E rekisoa e le letlapa la 5-milligram le bitsoang Erimin, lebitso la lebitso le entsoeng le ho rekisoa ke Sumitomo, k'hamphani e kholo ea Majapane.Japane ke eona feela naha lefatšeng e hlahisang nimetazepam.Ka ntle ho Japane, Erimin e fumaneha boholo ba Asia Bochabela le Boroa-bochabela 'me e sebelisoa haholo e le phekolo ea nakoana bakeng sa batho ba nang le bothata ba ho hlobaela haholo ba thatafalloang ke ho robala kapa ho robala.Sumitomo e emisitse ho etsa Erimin ho tloha ka November 2015. E ntse e fumaneha e le generic kapa Lavol.

Nimetazepam e ne e laetsoe haholo lilemong tsa bo-1980 le bo-1990, haholo-holo Japane, Malaysia, Brunei, Philippines, Thailand, Indonesia, Hong Kong le Singapore.Kaha tlhekefetso le bokhoba ba tahi li atile, litaelo tsa lithethefatsi li theohile haholo ho tloha 2005. E sebelisoa haholo-holo e le anticonvulsant ho bana.E boetse e ntse e sebelisoa maemong a matla ka ho fetesisa le a fokolisang a ho hlobaela ho Inpatient Settings kapa kalafo ea nako e khuts'oane ea kantle ho naha.Bakeng sa morero ona, lipilisi tsa boroko tsa benzodiazepines Esazolam le nitrazepam li ne li sebelisoa khafetsa ho feta nitrazepam.Li-antidepressants tse kang trazodone le mirtazapine kapa Zopiclone le zolpidem ke meriana ea pele bakeng sa lefu la ho hlobaela.

Leha lengolo la ngaka la nimetazepam le fokotsehile, tšebeliso e mpe ea lithethefatsi e ntse e le holimo Brunei, Singapore, Malaysia le Philippines.Hangata e sebelisoa hammoho le methamphetamine le ecstasy, hammoho le opioids (haholo-holo heroine kapa morphine).Nimetazepam e tlas'a lithibelo tse thata tsa molao Malaysia, tse entseng hore lithethefatsi li haelle, empa lipilisi tse ngata tse rekisoang 'marakeng o motšo tlas'a lebitso la Nimetazepam ke tsa maiketsetso.Diazepam le nitrazepam ke tse ling tsa li-benzodiazepine tse sebelisoang haholo tikolohong eo, 'me ka hona, hangata li khelosoa le ho rekisoa' marakeng o motšo, hangata joalo ka nitrazepam.

Tlhahiso e seng molaong ea Nimezepam (e rekisoang e le Erimin-5) e atile sebakeng seo.Tšebeliso e mpe ea nimetazepam e ile ea tsoela pele ho eketseha ho pholletsa le lilemo tsa 2010.Ho ts'oaroa ha matlapa a Erimin-5 a entsoeng ka tsela e seng molaong ho tsamaellana le ho ts'oaroa ha methamphetamine naheng ea Malaysia.Palo e nyane ea matlapa a 46 a seng molaong a Erimin-5 a nkiloeng a ile a lekoa bakeng sa thepa ea bona ea 'mele le ea lik'hemik'hale.Motsoako o sebetsang, dopant, diluent e ka sehloohong le dae ke likarolo tsa lik'hemik'hale tsa letlapa.Liphetho li bonts'a hore Nimetazepam e ne e le motsoako o sebetsang ka ho fetesisa oa matlapa a mangata a nkiloeng.Lactose e ile ea fumanoa e le eona e hlapollang e ka sehloohong lisampoleng tse ngata, ea lateloa ke mannitol, hamorao ke dicalcium phosphate dihydrate.Letsatsi le lesehla le likela le ile la fumanoa lisampoleng tse ngata tsa lipilisi, tse sebelisoang li le mong kapa li kopantsoe le lidae tse ling (mohlala, tartar le Lichenol 4R) ho fa pilisi 'mala oa perekisi/lamunu.Matlapa a matala a sampoleng a ne a e-na le lidae tse boputsoa bo khanyang le tartar.Diazepam haholo-holo ke sethethefatsi se thibelang ho tšoenyeha 'me ke motsoako o sebetsang ho letlapa le le leng feela la 46.Nitrazepam, sedative se matla le hypnotic le sethethefatsi sa motsoali sa nitrazepam, se fumanoe e le motsoako oa bobeli, ka caffeine e le karolo e ka sehloohong e kopantsoeng matlapeng a mararo.

Ka 2003, Singapore e ile ea hapa matlapa a Erimin-5 a 94 200.Laboratori ea Boto e Bohareng ea Narcotics (CNB) e ile ea etsa liteko matlapeng 'me liphetho li tiisa hore ehlile ke nitrazepam.