China e fana ka Lidocaine CAS 137-58-6 ka Theko e Molemohali
Litaba tsa Motheo
e qhibilihang ka har'a ethanol, ether, benzene, chloroform le oli, 'me ha e qhibilihe ka metsing.Hydrochloride e sebelisoang ka tloaelo, lidocaine hydrochloride (C14H22N2O·HCL, [73-78-9]) ke phofo e tšoeu ea kristale.Sebaka se qhibilihang ke 127-129 ℃, 'me sebaka se qhibilihisang sa monohydrate ke 77-78 ℃.E qhibiliha haholo metsing, 0.5% aqueous pHO4.0-5.5.Tatso ea hemp e sa nkheng, e babang.
Tšebeliso
Sehlahisoa ke sethethefatsi sa lehae sa amide.E sebelisoa haholo ho anesthesia ea holim'a metsi, anesthesia ea ho kenella, anesthesia ea conduction le epidural anesthesia.LD50 ea lidocaine hydrochloride e ne e le 290mg/kg.
Lisebelisoa tsa kliniki li kenyelletsa anesthesia ea ho kenella, epidURAL anesthesia, anesthesia ea ka holimo (ho kenyeletsoa anesthesia ea mucosal nakong ea thoracoscopy kapa opereishene ea mpa), le thibelo ea methapo.Epinephrine e ka kenyelletsoa ho thethebatso ho lelefatsa nako ea anesthesia le ho fokotsa litla-morao tse kang chefo ea lidocaine.
Lidocaine e ka boela ea sebelisoa ho phekola lefu la ventricular arrhythmias ka mor'a hore ho be le lefu le matla la myocardial infarction, ho kopanyelletsa le li-contraction tsa pele ho nako, tachycardia ea ventricular, ventricular arrhythmias e bakoang ke chefo ea digitalis, opereishene ea pelo le catheterization ea pelo, ho akarelletsa le ventricular premature contractions, ventricular tachycardia le tachycardia.E boetse e sebelisoa ho bakuli ba nang le boemo ba lefu la sethoathoa ba sa arabeleng li-anticonvulsants tse ling le bakeng sa anesthesia ea sebakeng seo kapa ea intraspinal.Hangata ha e sebetse khahlanong le supraventricular arrhythmias.
Litlhaloso
| Lebitso la Sehlahiswa | Lidocaine |
| CAS | 137-58-6 |
| MF | Setšoantšo sa C14H22N2O |
| MW | 234.34 |
| EINECS | 205-302-8 |
| Sebaka se qhibilihang | 66-69°C |
| Ntho e belang | bp4 180-182°;bp2 159-160° |
| tekano | 0.9944 (khakanyo e fosahetseng) |
| index ea refractive | 1.5110 (khakanyo) |
| Fp | 9℃ |
| mocheso oa polokelo. | Lebenkele ho RT |
| ho qhibiliha | ethanol: 4 mg/mL |
| pka | pKa 7.88(H2O)(Kakaretso) |
| sebopeho | phofo |
| mmala | Bosoeu ho isa ho mosehla hanyane |
| Ho qhibiliha ha Metsi | e batlang e sa qhibidihe |
| Merck | 14,5482 |
| Botsitso: | E tsitsitseng.Ha e lumellane le lisebelisoa tse matla tsa oxidizing. |
| InChIKey | NNJVILVZKWQKPM-UHFFFAOYSA-N |
| Referense ea CAS DataBase | 137-58-6(CAS DataBase Reference) |